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DNA vaccines: improving expression of antigens

Overview of attention for article published in Genetic Vaccines and Therapy, September 2003
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)

Mentioned by

twitter
1 X user
patent
11 patents
wikipedia
2 Wikipedia pages

Citations

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105 Dimensions

Readers on

mendeley
145 Mendeley
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Title
DNA vaccines: improving expression of antigens
Published in
Genetic Vaccines and Therapy, September 2003
DOI 10.1186/1479-0556-1-2
Pubmed ID
Authors

Helen S Garmory, Katherine A Brown, Richard W Titball

Abstract

DNA vaccination is a relatively recent development in vaccine methodology. It is now possible to undertake a rational step-by-step approach to DNA vaccine design. Strategies may include the incorporation of immunostimulatory sequences in the backbone of the plasmid, co-expression of stimulatory molecules, utilisation of localisation/secretory signals, and utilisation of the appropriate delivery system, for example. However, another important consideration is the utilisation of methods designed to optimise transgene expression. In this review we discuss the importance of regulatory elements, kozak sequences and codon optimisation in transgene expression.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 145 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 2 1%
Brazil 2 1%
Germany 1 <1%
Malaysia 1 <1%
United Kingdom 1 <1%
United States 1 <1%
Unknown 137 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 27 19%
Student > Master 23 16%
Student > Ph. D. Student 20 14%
Student > Postgraduate 14 10%
Student > Bachelor 13 9%
Other 30 21%
Unknown 18 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 61 42%
Biochemistry, Genetics and Molecular Biology 24 17%
Medicine and Dentistry 16 11%
Immunology and Microbiology 8 6%
Veterinary Science and Veterinary Medicine 4 3%
Other 9 6%
Unknown 23 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2024.
All research outputs
#2,202,161
of 25,374,647 outputs
Outputs from Genetic Vaccines and Therapy
#1
of 45 outputs
Outputs of similar age
#2,211
of 46,958 outputs
Outputs of similar age from Genetic Vaccines and Therapy
#1
of 1 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 45 research outputs from this source. They receive a mean Attention Score of 4.6. This one scored the same or higher as 44 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 46,958 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them