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Development and validation of a Diabetes Risk Score for screening undiagnosed diabetes in Sri Lanka (SLDRISK)

Overview of attention for article published in BMC Endocrine Disorders, July 2016
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Title
Development and validation of a Diabetes Risk Score for screening undiagnosed diabetes in Sri Lanka (SLDRISK)
Published in
BMC Endocrine Disorders, July 2016
DOI 10.1186/s12902-016-0124-8
Pubmed ID
Authors

P. Katulanda, N. R. Hill, I. Stratton, R. Sheriff, S. D. N. De Silva, D. R. Matthews

Abstract

Screening for undiagnosed diabetes is not widely undertaken due to the high costs and invasiveness of blood sampling. Simple non-invasive tools to identify high risk individuals can facilitate screening. The main objectives of this study are to develop and validate a risk score for screening undiagnosed diabetes among Sri Lankan adults and to compare its performance with the Cambridge Risk Score (CRS), the Indian Diabetes Risk Score (IDRS) and three other Asian risk scores. Data were available from a representative sample of 4276 adults without diagnosed diabetes. In a jack-knife approach two thirds of the sample was used for the development of the risk score and the remainder for the validation. Age, waist circumference, BMI, hypertension, balanitis or vulvitis, family history of diabetes, gestational diabetes, physical activity and osmotic symptoms were significantly associated with undiagnosed diabetes (age most to osmotic symptoms least). Individual scores were generated for these factors using the beta coefficient values obtained in multiple logistic regression. A cut-off value of sum = 31 was determined by ROC curve analysis. The area under the ROC curve of the risk score for prevalent diabetes was 0.78 (CI 0.73-0.82). In the sample 36.3 % were above the cut-off of 31. A risk score above 31 gave a sensitivity, specificity, positive predictive value and negative predictive value of 77.9, 65.6, 9.4 and 98.3 % respectively. For Sri Lankans the AUC for the CRS and IDRS were 0.72 and 0.66 repectively. This simple non-invasive screening tool can identify 80 % of undiagnosed diabetes by selecting 40 % of Sri Lankan adults for confirmatory blood investigations.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 75 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 16%
Student > Master 12 16%
Student > Ph. D. Student 9 12%
Student > Postgraduate 6 8%
Student > Bachelor 4 5%
Other 15 20%
Unknown 17 23%
Readers by discipline Count As %
Medicine and Dentistry 28 37%
Nursing and Health Professions 12 16%
Social Sciences 4 5%
Biochemistry, Genetics and Molecular Biology 3 4%
Agricultural and Biological Sciences 2 3%
Other 9 12%
Unknown 17 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2016.
All research outputs
#9,837,306
of 15,466,991 outputs
Outputs from BMC Endocrine Disorders
#210
of 401 outputs
Outputs of similar age
#149,318
of 266,205 outputs
Outputs of similar age from BMC Endocrine Disorders
#1
of 1 outputs
Altmetric has tracked 15,466,991 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 401 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,205 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them