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Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions

Overview of attention for article published in BMC Genomics, October 2012
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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4 X users

Citations

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49 Dimensions

Readers on

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48 Mendeley
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4 CiteULike
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Title
Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions
Published in
BMC Genomics, October 2012
DOI 10.1186/1471-2164-13-563
Pubmed ID
Authors

Yanhai Guo, Wei Kang, Xiaoying Lei, Yongnian Li, An Xiang, Yonglan Liu, Jinrong Zhao, Ju Zhang, Zhen Yan

Abstract

The core protein (HBc) of hepatitis B virus (HBV) has been implicated in the malignant transformation of chronically-infected hepatocytes and displays pleiotropic functions, including RNA- and DNA-binding activities. However, the mechanism by which HBc interacts with the human genome to exert effects on hepatocyte function remains unknown. This study investigated the distribution of HBc binding to promoters in the human genome and evaluated its effects on the related genes' expression.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 47 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 25%
Researcher 12 25%
Student > Ph. D. Student 9 19%
Other 4 8%
Student > Postgraduate 2 4%
Other 3 6%
Unknown 6 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 29%
Medicine and Dentistry 12 25%
Agricultural and Biological Sciences 9 19%
Immunology and Microbiology 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 3 6%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2012.
All research outputs
#14,913,296
of 25,371,288 outputs
Outputs from BMC Genomics
#5,157
of 11,244 outputs
Outputs of similar age
#114,786
of 200,489 outputs
Outputs of similar age from BMC Genomics
#82
of 186 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,489 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 186 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.