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Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions

Overview of attention for article published in BMC Genomics, January 2012
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Mentioned by

twitter
3 tweeters

Citations

dimensions_citation
44 Dimensions

Readers on

mendeley
46 Mendeley
citeulike
4 CiteULike
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Title
Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions
Published in
BMC Genomics, January 2012
DOI 10.1186/1471-2164-13-563
Pubmed ID
Authors

Yanhai Guo, Wei Kang, Xiaoying Lei, Yongnian Li, An Xiang, Yonglan Liu, Jinrong Zhao, Ju Zhang, Zhen Yan

Abstract

The core protein (HBc) of hepatitis B virus (HBV) has been implicated in the malignant transformation of chronically-infected hepatocytes and displays pleiotropic functions, including RNA- and DNA-binding activities. However, the mechanism by which HBc interacts with the human genome to exert effects on hepatocyte function remains unknown. This study investigated the distribution of HBc binding to promoters in the human genome and evaluated its effects on the related genes' expression.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 24%
Researcher 11 24%
Student > Ph. D. Student 9 20%
Other 4 9%
Unspecified 2 4%
Other 5 11%
Unknown 4 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 28%
Medicine and Dentistry 11 24%
Agricultural and Biological Sciences 9 20%
Immunology and Microbiology 3 7%
Unspecified 2 4%
Other 4 9%
Unknown 4 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2012.
All research outputs
#13,875,295
of 22,684,168 outputs
Outputs from BMC Genomics
#5,318
of 10,613 outputs
Outputs of similar age
#151,734
of 244,115 outputs
Outputs of similar age from BMC Genomics
#148
of 295 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,613 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,115 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 295 others from the same source and published within six weeks on either side of this one. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.