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X Demographics
Mendeley readers
Attention Score in Context
| Title |
N-Acetyl-Cysteine Causes Analgesia by Reinforcing the Endogenous Activation of Type-2 Metabotropic Glutamate Receptors
|
|---|---|
| Published in |
Molecular Pain, January 2012
|
| DOI | 10.1186/1744-8069-8-77 |
| Pubmed ID | |
| Authors |
Matteo Bernabucci, Serena Notartomaso, Cristina Zappulla, Francesco Fazio, Milena Cannella, Marta Motolese, Giuseppe Battaglia, Valeria Bruno, Roberto Gradini, Ferdinando Nicoletti |
| Abstract |
Pharmacological activation of type-2 metabotropic glutamate receptors (mGlu2 receptors) causes analgesia in experimental models of inflammatory and neuropathic pain. Presynaptic mGlu2 receptors are activated by the glutamate released from astrocytes by means of the cystine/glutamate antiporter (System x(c)(-) or Sx(c)(-)). We examined the analgesic activity of the Sx(c)(-) activator, N-acetyl-cysteine (NAC), in mice developing inflammatory or neuropathic pain. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 20% |
| Researcher | 6 | 13% |
| Professor > Associate Professor | 6 | 13% |
| Student > Bachelor | 3 | 7% |
| Student > Master | 3 | 7% |
| Other | 6 | 13% |
| Unknown | 12 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 10 | 22% |
| Agricultural and Biological Sciences | 8 | 18% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 9% |
| Neuroscience | 4 | 9% |
| Biochemistry, Genetics and Molecular Biology | 2 | 4% |
| Other | 5 | 11% |
| Unknown | 12 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2022.
All research outputs
#8,535,684
of 25,374,917 outputs
Outputs from Molecular Pain
#190
of 669 outputs
Outputs of similar age
#73,504
of 250,099 outputs
Outputs of similar age from Molecular Pain
#16
of 47 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,099 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.