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New perspectives on central and peripheral immune responses to acute traumatic brain injury

Overview of attention for article published in Journal of Neuroinflammation, October 2012
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Title
New perspectives on central and peripheral immune responses to acute traumatic brain injury
Published in
Journal of Neuroinflammation, October 2012
DOI 10.1186/1742-2094-9-236
Pubmed ID
Authors

Mahasweta Das, Subhra Mohapatra, Shyam S Mohapatra

Abstract

Traumatic injury to the brain (TBI) results in a complex set of responses involving various symptoms and long-term consequences. TBI of any form can cause cognitive, behavioral and immunologic changes in later life, which underscores the problem of underdiagnosis of mild TBI that can cause long-term neurological deficits. TBI disrupts the blood-brain barrier (BBB) leading to infiltration of immune cells into the brain and subsequent inflammation and neurodegeneration. TBI-induced peripheral immune responses can also result in multiorgan damage. Despite worldwide research efforts, the methods of diagnosis, monitoring and treatment for TBI are still relatively ineffective. In this review, we delve into the mechanism of how TBI-induced central and peripheral immune responses affect the disease outcome and discuss recent developments in the continuing effort to combat the consequences of TBI and new ways to enhance repair of the damaged brain.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 238 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 <1%
United States 2 <1%
Netherlands 1 <1%
Egypt 1 <1%
Canada 1 <1%
Unknown 231 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 41 17%
Researcher 41 17%
Student > Bachelor 29 12%
Student > Master 23 10%
Student > Doctoral Student 21 9%
Other 35 15%
Unknown 48 20%
Readers by discipline Count As %
Medicine and Dentistry 62 26%
Agricultural and Biological Sciences 37 16%
Neuroscience 36 15%
Biochemistry, Genetics and Molecular Biology 13 5%
Psychology 9 4%
Other 30 13%
Unknown 51 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2012.
All research outputs
#20,171,868
of 22,684,168 outputs
Outputs from Journal of Neuroinflammation
#2,288
of 2,608 outputs
Outputs of similar age
#153,741
of 173,083 outputs
Outputs of similar age from Journal of Neuroinflammation
#21
of 24 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,608 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,083 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.