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Direct photo-patterning on anthracene containing polymer for guiding stem cell adhesion

Overview of attention for article published in Biomaterials Research, January 2016
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2 tweeters

Citations

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6 Dimensions

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10 Mendeley
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Title
Direct photo-patterning on anthracene containing polymer for guiding stem cell adhesion
Published in
Biomaterials Research, January 2016
DOI 10.1186/s40824-016-0072-4
Pubmed ID
Authors

You, Jungmok, Heo, June Seok, Kim, Hyun Ok, Kim, Eunkyoumg

Abstract

Various micropatterned surfaces capable of guiding the selective adhesion of biomolecules such as proteins and cells are of great interests in biosensor, diagnostics, drug screening, and tissue engineering. In this study, we described a simple photo-patterning method to prepare micro-patterned films for stem cell patterning using anthracene containing polymers (PMAn). This micro patterned polymer film was prepared by the facile photo-reaction of anthracene units in polymer backbone structure. The UV irradiation of PMAn through a photomask resulted in the quenching of fluorescent intensity as well as the changes in surface wettability from hydrophobic to hydrophilic surface. As a result, UV exposed regions of PMAn film show lower fluorescent intensity as well as higher proliferation rate of mesenchymal stem cells (MSCs) than unexposed region of PMAn film. Furthermore, the selective MSC attachment was clearly observed in the UV exposed regions of PMAn film. We developed a simple cell patterning method with a fluorescent, biocompatible, and patternable polymer film containing anthracene units. This method provides a facile stem cell patterning method and could be extended to various patterning of biomaterials without labor-intensive preparation and no pre-treatment for complex interactions of cell-microenvironment.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 30%
Student > Doctoral Student 2 20%
Student > Bachelor 2 20%
Researcher 1 10%
Student > Postgraduate 1 10%
Other 0 0%
Unknown 1 10%
Readers by discipline Count As %
Materials Science 4 40%
Computer Science 1 10%
Chemical Engineering 1 10%
Chemistry 1 10%
Unknown 3 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2016.
All research outputs
#4,093,464
of 8,170,298 outputs
Outputs from Biomaterials Research
#10
of 30 outputs
Outputs of similar age
#129,637
of 257,063 outputs
Outputs of similar age from Biomaterials Research
#3
of 3 outputs
Altmetric has tracked 8,170,298 research outputs across all sources so far. This one is in the 47th percentile – i.e., 47% of other outputs scored the same or lower than it.
So far Altmetric has tracked 30 research outputs from this source. They receive a mean Attention Score of 2.4. This one scored the same or higher as 20 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 257,063 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.