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HIV-1 infection is associated with changes in nuclear receptor transcriptome, pro-inflammatory and lipid profile of monocytes

Overview of attention for article published in BMC Infectious Diseases, October 2012
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Title
HIV-1 infection is associated with changes in nuclear receptor transcriptome, pro-inflammatory and lipid profile of monocytes
Published in
BMC Infectious Diseases, October 2012
DOI 10.1186/1471-2334-12-274
Pubmed ID
Authors

Barbara Renga, Daniela Francisci, Claudio D’Amore, Elisabetta Schiaroli, Adriana Carino, Franco Baldelli, Stefano Fiorucci

Abstract

Persistent residual immune activation and lipid dysmetabolism are characteristics of HIV positive patients receiving an highly active antiretroviral therapy (HAART). Nuclear Receptors are transcription factors involved in the regulation of immune and metabolic functions through the modulation of gene transcription. The objective of the present study was to investigate for the relative abundance of members of the nuclear receptor family in monocytic cells isolated from HIV positive patients treated or not treated with HAART.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 2 4%
United States 2 4%
United Kingdom 1 2%
Unknown 45 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 22%
Student > Ph. D. Student 9 18%
Student > Master 8 16%
Student > Bachelor 6 12%
Student > Postgraduate 3 6%
Other 6 12%
Unknown 7 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 28%
Medicine and Dentistry 10 20%
Biochemistry, Genetics and Molecular Biology 8 16%
Immunology and Microbiology 5 10%
Neuroscience 2 4%
Other 4 8%
Unknown 7 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2012.
All research outputs
#20,171,868
of 22,684,168 outputs
Outputs from BMC Infectious Diseases
#6,424
of 7,643 outputs
Outputs of similar age
#163,453
of 183,629 outputs
Outputs of similar age from BMC Infectious Diseases
#104
of 136 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,643 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,629 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 136 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.