Title |
Physiology versus evidence-based guidance for critical care practice
|
---|---|
Published in |
Critical Care, December 2015
|
DOI | 10.1186/cc14725 |
Pubmed ID | |
Authors |
Luciano Gattinoni, Eleonora Carlesso, Alessandro Santini |
Abstract |
Evidence based medicine is an attempt to optimize the medical decision process through methods primarily based on evidence coming from meta-analyses, systematic reviews, and randomized controlled trials ("evidence-based medicine"), rather than on "clinical judgment" alone. The randomized trials are the cornerstones of this process. However, the randomized trials are just a method to prove or disprove a given hypothesis, which, in turn, derives from a general observation of the reality (premises or theories). In this paper we will examine some of the most recent randomized trials performed in Intensive Care, analyzing their premises, hypothesis and outcome. It is quite evident that when the premises are wrong or too vague the unavoidable consequences will be a negative outcome. We should pay when designing the trial an equal attention in defining premises and hypothesis that we pay for the trial conduction. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 10 | 19% |
Mexico | 3 | 6% |
Chile | 2 | 4% |
United Kingdom | 2 | 4% |
Norway | 2 | 4% |
Morocco | 1 | 2% |
Austria | 1 | 2% |
Italy | 1 | 2% |
France | 1 | 2% |
Other | 10 | 19% |
Unknown | 20 | 38% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 30 | 57% |
Practitioners (doctors, other healthcare professionals) | 12 | 23% |
Scientists | 8 | 15% |
Science communicators (journalists, bloggers, editors) | 3 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 2 | 5% |
United Kingdom | 1 | 2% |
Unknown | 41 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 7 | 16% |
Researcher | 7 | 16% |
Student > Master | 5 | 11% |
Student > Bachelor | 4 | 9% |
Student > Ph. D. Student | 4 | 9% |
Other | 10 | 23% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 64% |
Neuroscience | 2 | 5% |
Agricultural and Biological Sciences | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Social Sciences | 1 | 2% |
Other | 1 | 2% |
Unknown | 10 | 23% |