Title |
Mortality in members of HIV-1 serodiscordant couples in Africa and implications for antiretroviral therapy initiation: Results of analyses from a multicenter randomized trial
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Published in |
BMC Infectious Diseases, October 2012
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DOI | 10.1186/1471-2334-12-277 |
Pubmed ID | |
Authors |
Guy de Bruyn, Amalia Magaret, Jared M Baeten, Jairam R Lingappa, Patrick Ndase, Connie Celum, Anna Wald, for the Partners in Prevention HSV/HIV Transmission Study Team |
Abstract |
The risk of HIV-1 related mortality is strongly related to CD4 count. Guidance on optimal timing for initiation of antiretroviral therapy (ART) is still evolving, but the contribution of HIV-1 infection to excess mortality at CD4 cell counts above thresholds for HIV-1 treatment has not been fully described, especially in resource-poor settings. To compare mortality among HIV-1 infected and uninfected members of HIV-1 serodiscordant couples followed for up to 24 months, we conducted a secondary data analysis examining mortality among HIV-1 serodiscordant couples participating in a multicenter, randomized controlled trial at 14 sites in seven sub-Saharan African countries. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 43% |
Unknown | 4 | 57% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 86% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
Ethiopia | 1 | 2% |
Unknown | 58 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 10 | 17% |
Student > Master | 8 | 13% |
Student > Ph. D. Student | 7 | 12% |
Student > Doctoral Student | 4 | 7% |
Lecturer | 3 | 5% |
Other | 9 | 15% |
Unknown | 19 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 32% |
Social Sciences | 5 | 8% |
Nursing and Health Professions | 4 | 7% |
Agricultural and Biological Sciences | 3 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
Other | 5 | 8% |
Unknown | 21 | 35% |