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The juice of fresh leaves of Catharanthus roseus Linn. reduces blood glucose in normal and alloxan diabetic rabbits

Overview of attention for article published in BMC Complementary Medicine and Therapies, September 2003
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)

Mentioned by

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2 news outlets
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1 X user
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1 Facebook page
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1 YouTube creator

Citations

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128 Dimensions

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127 Mendeley
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Title
The juice of fresh leaves of Catharanthus roseus Linn. reduces blood glucose in normal and alloxan diabetic rabbits
Published in
BMC Complementary Medicine and Therapies, September 2003
DOI 10.1186/1472-6882-3-4
Pubmed ID
Authors

Srinivas Nammi, Murthy K Boini, Srinivas D Lodagala, Ravindra Babu S Behara

Abstract

The leaf juice or water decoction of Catharanthus roseus L. (Apocyanaceae) is used as a folk medicine for the treatment of diabetes all over the world. In the present investigation, the leaf juice of C. roseus has been evaluated for its hypoglycemic activity in normal and alloxan-induced diabetic rabbits. The blood glucose lowering activity of the leaf juice was studied in normal and alloxan-induced (100 mg/kg, i.v.) diabetic rabbits, after oral administration at doses of 0.5, 0.75 and 1.0 ml/kg body weight. Blood samples were collected from the marginal ear vein before and also at 4, 6, 8, 10, 12, 16, 18, 20 & 24 h after drug administration and blood glucose was analyzed by Nelson-Somogyi's method using a visible spectrophotometer. The data was compared statistically by using Student's t-test. The leaf juice of C. roseus produced dose-dependent reduction in blood glucose of both normal and diabetic rabbits and comparable with that of the standard drug, glibenclamide. The results indicate a prolonged action in reduction of blood glucose by C. roseus and the mode of action of the active compound(s) of C. roseus is probably mediated through enhance secretion of insulin from the beta-cells of Langerhans or through extrapancreatic mechanism. The present study clearly indicated a significant antidiabetic activity with the leaf juice of Catharanthus roseus and supports the traditional usage of the fresh leaves by Ayurvedic physicians for the control of diabetes.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 <1%
Australia 1 <1%
South Africa 1 <1%
India 1 <1%
Iran, Islamic Republic of 1 <1%
United States 1 <1%
Unknown 121 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 15%
Student > Master 14 11%
Student > Ph. D. Student 12 9%
Student > Doctoral Student 10 8%
Researcher 9 7%
Other 23 18%
Unknown 40 31%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 20%
Pharmacology, Toxicology and Pharmaceutical Science 19 15%
Biochemistry, Genetics and Molecular Biology 11 9%
Medicine and Dentistry 10 8%
Chemistry 7 6%
Other 6 5%
Unknown 49 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2023.
All research outputs
#1,528,248
of 23,578,918 outputs
Outputs from BMC Complementary Medicine and Therapies
#253
of 3,707 outputs
Outputs of similar age
#1,590
of 50,572 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#1
of 1 outputs
Altmetric has tracked 23,578,918 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,707 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 50,572 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them