Title |
Encapsulation of gold nanoparticles into self-assembling protein nanoparticles
|
---|---|
Published in |
Journal of Nanobiotechnology, October 2012
|
DOI | 10.1186/1477-3155-10-42 |
Pubmed ID | |
Authors |
Yongkun Yang, Peter Burkhard |
Abstract |
Gold nanoparticles are useful tools for biological applications due to their attractive physical and chemical properties. Their applications can be further expanded when they are functionalized with biological molecules. The biological molecules not only provide the interfaces for interactions between nanoparticles and biological environment, but also contribute their biological functions to the nanoparticles. Therefore, we used self-assembling protein nanoparticles (SAPNs) to encapsulate gold nanoparticles. The protein nanoparticles are formed upon self-assembly of a protein chain that is composed of a pentameric coiled-coil domain at the N-terminus and trimeric coiled-coil domain at the C-terminus. The self-assembling protein nanoparticles form a central cavity of about 10 nm in size, which is ideal for the encapsulation of gold nanoparticles with similar sizes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 1% |
Indonesia | 1 | 1% |
France | 1 | 1% |
South Africa | 1 | 1% |
India | 1 | 1% |
United States | 1 | 1% |
Unknown | 85 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 29 | 32% |
Researcher | 14 | 15% |
Student > Master | 13 | 14% |
Student > Bachelor | 4 | 4% |
Lecturer | 4 | 4% |
Other | 16 | 18% |
Unknown | 11 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 22 | 24% |
Agricultural and Biological Sciences | 17 | 19% |
Biochemistry, Genetics and Molecular Biology | 12 | 13% |
Materials Science | 7 | 8% |
Medicine and Dentistry | 6 | 7% |
Other | 9 | 10% |
Unknown | 18 | 20% |