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Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent

Overview of attention for article published in BMC Research Notes, September 2012
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Title
Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent
Published in
BMC Research Notes, September 2012
DOI 10.1186/1756-0500-5-497
Pubmed ID
Authors

Laith N AL-Eitan, Saied A Jaradat, Gary K Hulse, Guan K Tay

Abstract

Both environmental and genetic factors contribute to individual susceptibility to initiation of substance use and vulnerability to addiction. Determining genetic risk factors can make an important contribution to understanding the processes leading to addiction. In order to identify gene(s) and mechanisms associated with substance addiction, a custom platform array search for a genetic association in a case/control of homogenous Jordanian Arab population was undertaken. Patients meeting the DSM-VI criteria for substance dependence (n = 220) and entering eight week treatment program at two Jordanian Drug Rehabilitation Centres were genotyped. In addition, 240 healthy controls were also genotyped. The sequenom MassARRAY system (iPLEX GOLD) was used to genotype 49 single nucleotide polymorphisms (SNPs) within 8 genes (DRD1, DRD2, DRD3, DRD4, DRD5, BDNF, SLC6A3 and COMT).

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 12%
Student > Bachelor 5 12%
Other 4 10%
Student > Master 4 10%
Student > Ph. D. Student 3 7%
Other 10 24%
Unknown 11 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 14%
Agricultural and Biological Sciences 6 14%
Medicine and Dentistry 5 12%
Social Sciences 4 10%
Psychology 2 5%
Other 6 14%
Unknown 13 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2012.
All research outputs
#15,255,201
of 22,684,168 outputs
Outputs from BMC Research Notes
#2,310
of 4,253 outputs
Outputs of similar age
#106,048
of 168,267 outputs
Outputs of similar age from BMC Research Notes
#58
of 92 outputs
Altmetric has tracked 22,684,168 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,253 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,267 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.