↓ Skip to main content

Paradigm shift: the primary function of the “Adiponectin Receptors” is to regulate cell membrane composition

Overview of attention for article published in Lipids in Health and Disease, April 2021
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

twitter
2 X users
f1000
1 research highlight platform

Citations

dimensions_citation
21 Dimensions

Readers on

mendeley
36 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Paradigm shift: the primary function of the “Adiponectin Receptors” is to regulate cell membrane composition
Published in
Lipids in Health and Disease, April 2021
DOI 10.1186/s12944-021-01468-y
Pubmed ID
Authors

Marc Pilon

Abstract

The ADIPOR1 and ADIPOR2 proteins (ADIPORs) are generally considered as adiponectin receptors with anti-diabetic properties. However, studies on the yeast and C. elegans homologs of the mammalian ADIPORs, and of the ADIPORs themselves in various mammalian cell models, support an updated/different view. Based on findings in these experimental models, the ADIPORs are now emerging as evolutionarily conserved regulators of membrane homeostasis that do not require adiponectin to act as membrane fluidity sensors and regulate phospholipid composition. More specifically, membrane rigidification activates ADIPOR signaling to promote fatty acid desaturation and incorporation of polyunsaturated fatty acids into membrane phospholipids until fluidity is restored. The present review summarizes the evidence supporting this new view of the ADIPORs, and briefly examines physiological consequences.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 19%
Researcher 5 14%
Unspecified 3 8%
Student > Doctoral Student 2 6%
Student > Bachelor 2 6%
Other 5 14%
Unknown 12 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 19%
Medicine and Dentistry 4 11%
Unspecified 3 8%
Agricultural and Biological Sciences 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 4 11%
Unknown 15 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2021.
All research outputs
#14,554,120
of 23,308,124 outputs
Outputs from Lipids in Health and Disease
#697
of 1,476 outputs
Outputs of similar age
#227,417
of 437,141 outputs
Outputs of similar age from Lipids in Health and Disease
#4
of 18 outputs
Altmetric has tracked 23,308,124 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,476 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 437,141 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.