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Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult

Overview of attention for article published in Molecular Neurodegeneration, June 2012
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  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Average Attention Score compared to outputs of the same age and source

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1 X user
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1 patent
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1 Facebook page

Citations

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54 Dimensions

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80 Mendeley
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Title
Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult
Published in
Molecular Neurodegeneration, June 2012
DOI 10.1186/1750-1326-7-28
Pubmed ID
Authors

Shaefali P Rodgers, Heather A Born, Pritam Das, Joanna L Jankowsky

Abstract

Transgenic mice expressing disease-associated proteins have become standard tools for studying human neurological disorders. Transgenes are often expressed using promoters chosen to drive continuous high-level expression throughout life rather than temporal and spatial fidelity to the endogenous gene. This approach has allowed us to recapitulate diseases of aging within the two-year lifespan of the laboratory mouse, but has the potential for creating aberrant phenotypes by mechanisms unrelated to the human disorder.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 1%
Unknown 79 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 31%
Researcher 14 18%
Student > Master 12 15%
Student > Bachelor 7 9%
Professor > Associate Professor 4 5%
Other 8 10%
Unknown 10 13%
Readers by discipline Count As %
Neuroscience 24 30%
Agricultural and Biological Sciences 16 20%
Medicine and Dentistry 9 11%
Biochemistry, Genetics and Molecular Biology 5 6%
Psychology 5 6%
Other 7 9%
Unknown 14 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2023.
All research outputs
#7,449,640
of 24,041,016 outputs
Outputs from Molecular Neurodegeneration
#622
of 893 outputs
Outputs of similar age
#50,702
of 166,936 outputs
Outputs of similar age from Molecular Neurodegeneration
#8
of 11 outputs
Altmetric has tracked 24,041,016 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 893 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,936 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.