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Exosomal cell-to-cell transmission of alpha synuclein oligomers

Overview of attention for article published in Molecular Neurodegeneration, January 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

twitter
1 tweeter
patent
1 patent
facebook
1 Facebook page
reddit
1 Redditor

Citations

dimensions_citation
483 Dimensions

Readers on

mendeley
554 Mendeley
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Title
Exosomal cell-to-cell transmission of alpha synuclein oligomers
Published in
Molecular Neurodegeneration, January 2012
DOI 10.1186/1750-1326-7-42
Pubmed ID
Authors

Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg, Pamela J McLean

Abstract

Aggregation of alpha-synuclein (αsyn) and resulting cytotoxicity is a hallmark of sporadic and familial Parkinson's disease (PD) as well as dementia with Lewy bodies, with recent evidence implicating oligomeric and pre-fibrillar forms of αsyn as the pathogenic species. Recent in vitro studies support the idea of transcellular spread of extracellular, secreted αsyn across membranes. The aim of this study is to characterize the transcellular spread of αsyn oligomers and determine their extracellular location.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 554 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
United Kingdom 2 <1%
Italy 2 <1%
Canada 1 <1%
France 1 <1%
Australia 1 <1%
Egypt 1 <1%
Belgium 1 <1%
Russia 1 <1%
Other 3 <1%
Unknown 539 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 130 23%
Researcher 87 16%
Student > Master 80 14%
Student > Bachelor 76 14%
Student > Doctoral Student 31 6%
Other 78 14%
Unknown 72 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 152 27%
Biochemistry, Genetics and Molecular Biology 110 20%
Neuroscience 102 18%
Medicine and Dentistry 42 8%
Chemistry 14 3%
Other 45 8%
Unknown 89 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2018.
All research outputs
#4,731,079
of 16,951,449 outputs
Outputs from Molecular Neurodegeneration
#397
of 668 outputs
Outputs of similar age
#40,879
of 158,847 outputs
Outputs of similar age from Molecular Neurodegeneration
#2
of 8 outputs
Altmetric has tracked 16,951,449 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 668 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 158,847 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.