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Exosomal cell-to-cell transmission of alpha synuclein oligomers

Overview of attention for article published in Molecular Neurodegeneration, August 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user
patent
2 patents
facebook
1 Facebook page
reddit
1 Redditor

Citations

dimensions_citation
684 Dimensions

Readers on

mendeley
717 Mendeley
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Title
Exosomal cell-to-cell transmission of alpha synuclein oligomers
Published in
Molecular Neurodegeneration, August 2012
DOI 10.1186/1750-1326-7-42
Pubmed ID
Authors

Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg, Pamela J McLean

Abstract

Aggregation of alpha-synuclein (αsyn) and resulting cytotoxicity is a hallmark of sporadic and familial Parkinson's disease (PD) as well as dementia with Lewy bodies, with recent evidence implicating oligomeric and pre-fibrillar forms of αsyn as the pathogenic species. Recent in vitro studies support the idea of transcellular spread of extracellular, secreted αsyn across membranes. The aim of this study is to characterize the transcellular spread of αsyn oligomers and determine their extracellular location.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 717 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 2 <1%
United States 2 <1%
France 1 <1%
Chile 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
Egypt 1 <1%
Australia 1 <1%
Russia 1 <1%
Other 3 <1%
Unknown 703 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 158 22%
Researcher 101 14%
Student > Master 95 13%
Student > Bachelor 90 13%
Student > Doctoral Student 35 5%
Other 92 13%
Unknown 146 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 163 23%
Biochemistry, Genetics and Molecular Biology 133 19%
Neuroscience 127 18%
Medicine and Dentistry 52 7%
Chemistry 18 3%
Other 58 8%
Unknown 166 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2023.
All research outputs
#2,550,734
of 24,673,288 outputs
Outputs from Molecular Neurodegeneration
#327
of 929 outputs
Outputs of similar age
#16,324
of 175,413 outputs
Outputs of similar age from Molecular Neurodegeneration
#1
of 13 outputs
Altmetric has tracked 24,673,288 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 929 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.9. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,413 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.