Title |
Nurse-led group consultation intervention reduces depressive symptoms in men with localised prostate cancer: a cluster randomised controlled trial
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Published in |
BMC Cancer, August 2016
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DOI | 10.1186/s12885-016-2687-1 |
Pubmed ID | |
Authors |
Penelope Schofield, Karla Gough, Kerryann Lotfi-Jam, Rebecca Bergin, Anna Ugalde, Paul Dudgeon, Wallace Crellin, Kathryn Schubach, Farshard Foroudi, Keen Hun Tai, Gillian Duchesne, Rob Sanson-Fisher, Sanchia Aranda |
Abstract |
Radiotherapy for localised prostate cancer has many known and distressing side effects. The efficacy of group interventions for reducing psychological morbidity is lacking. This study investigated the relative benefits of a group nurse-led intervention on psychological morbidity, unmet needs, treatment-related concerns and prostate cancer-specific quality of life in men receiving curative intent radiotherapy for prostate cancer. This phase III, two-arm cluster randomised controlled trial included 331 men (consent rate: 72 %; attrition: 5 %) randomised to the intervention (n = 166) or usual care (n = 165). The intervention comprised four group and one individual consultation all delivered by specialist uro-oncology nurses. Primary outcomes were anxious and depressive symptoms as assessed by the Hospital Anxiety and Depression Scale. Unmet needs were assessed with the Supportive Care Needs Survey-SF34 Revised, treatment-related concerns with the Cancer Treatment Scale and quality of life with the Expanded Prostate Cancer Index -26. Assessments occurred before, at the end of and 6 months post-radiotherapy. Primary outcome analysis was by intention-to-treat and performed by fitting a linear mixed model to each outcome separately using all observed data. Mixed models analysis indicated that group consultations had a significant beneficial effect on one of two primary endpoints, depressive symptoms (p = 0.009), and one of twelve secondary endpoints, procedural concerns related to cancer treatment (p = 0.049). Group consultations did not have a significant beneficial effect on generalised anxiety, unmet needs and prostate cancer-specific quality of life. Compared with individual consultations offered as part of usual care, the intervention provides a means of delivering patient education and is associated with modest reductions in depressive symptoms and procedural concerns. Future work should seek to confirm the clinical feasibility and cost-effectiveness of group interventions. Australian and New Zealand Clinical Trials Registry ANZCTRN012606000184572 . 1 March 2006. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 185 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 30 | 16% |
Student > Bachelor | 26 | 14% |
Researcher | 14 | 8% |
Student > Postgraduate | 10 | 5% |
Student > Doctoral Student | 10 | 5% |
Other | 31 | 17% |
Unknown | 64 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 39 | 21% |
Medicine and Dentistry | 26 | 14% |
Psychology | 24 | 13% |
Social Sciences | 4 | 2% |
Sports and Recreations | 3 | 2% |
Other | 14 | 8% |
Unknown | 75 | 41% |