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Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging

Overview of attention for article published in BMC Developmental Biology, November 2012
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Citations

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38 Dimensions

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89 Mendeley
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Title
Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging
Published in
BMC Developmental Biology, November 2012
DOI 10.1186/1471-213x-12-32
Pubmed ID
Authors

János Barna, Andrea Princz, Mónika Kosztelnik, Balázs Hargitai, Krisztina Takács-Vellai, Tibor Vellai

Abstract

Temperature affects virtually all cellular processes. A quick increase in temperature challenges the cells to undergo a heat shock response to maintain cellular homeostasis. Heat shock factor-1 (HSF-1) functions as a major player in this response as it activates the transcription of genes coding for molecular chaperones (also called heat shock proteins) that maintain structural integrity of proteins. However, the mechanisms by which HSF-1 adjusts fundamental cellular processes such as growth, proliferation, differentiation and aging to the ambient temperature remain largely unknown.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 88 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 22%
Student > Bachelor 15 17%
Researcher 14 16%
Student > Master 9 10%
Professor > Associate Professor 6 7%
Other 11 12%
Unknown 14 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 43 48%
Biochemistry, Genetics and Molecular Biology 23 26%
Computer Science 2 2%
Business, Management and Accounting 1 1%
Social Sciences 1 1%
Other 3 3%
Unknown 16 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2012.
All research outputs
#19,292,491
of 23,881,329 outputs
Outputs from BMC Developmental Biology
#300
of 359 outputs
Outputs of similar age
#142,845
of 186,052 outputs
Outputs of similar age from BMC Developmental Biology
#4
of 5 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 359 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 186,052 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.