Title |
Overexpression of chemokine ligand 7 is associated with the progression of canine transmissible venereal tumor
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Published in |
BMC Veterinary Research, November 2012
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DOI | 10.1186/1746-6148-8-216 |
Pubmed ID | |
Authors |
Hsin-Chien Chiang, Yu-Shan Wang, Chung-Hsi Chou, Albert Taiching Liao, Rea-Min Chu, Chen-Si Lin |
Abstract |
Chemokines play multiple roles in the development and progression in a variety of tumors. Chemokine (C-X-C motif) ligand 7 (CXCL7) has been found associated with pro-inflammatory responses, but its role in cancer growth remains unclear. Our previous study showed that R phase tumor infiltrating lymphocytes (TILs) produced large amounts of interleukin (IL)-6 which antagonized transforming growth factor (TGF)-β derived from CTVT to diminish the immune-suppressive microenvironment. Now we intend to determine the expression pattern of CXCL7 and the role of IL-6/TGF-β in CXCL7 induction during spontaneous progressive (P) and regressive (R) phases in canine transmissible venereal tumor (CTVT). |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 3% |
Turkey | 1 | 3% |
United States | 1 | 3% |
Unknown | 36 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 6 | 15% |
Student > Bachelor | 6 | 15% |
Student > Master | 6 | 15% |
Other | 5 | 13% |
Student > Ph. D. Student | 3 | 8% |
Other | 9 | 23% |
Unknown | 4 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 14 | 36% |
Medicine and Dentistry | 8 | 21% |
Agricultural and Biological Sciences | 3 | 8% |
Engineering | 3 | 8% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Other | 6 | 15% |
Unknown | 3 | 8% |