Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process

Melatonin vs senescence: Stem cell rejuvenation — Long-term in vitro passaging led to human periodontal ligament #StemCell #senescence & impaired autophagy. #Melatonin restored cells to younger state & fixed #autophagy in senescent cells via PI3K/A