5-19-2021: Because Actemra (tocilizumab) is the all-purpose antioxidant, I would think that it would be even more beneficial to frail people than to strong people. In a study just released today from France, Actemra did well in treating age 80+ with GCA:
Assessment of the efficacy and safety of tocilizumab in patients over 80 years old with giant cell arteritis - Arthritis Res Ther https://t.co/pjGzXlh7b8
Real world study of 21 GCA patients over age 80 yrs taking tocilizumab. (for GC-sparing in 14, relapsing Dz in 8, severity in 4, DMARD failure in 4). 8 [2–21] months post-TCZ, 67% were off GCs. AE included 4 Hi Chol, 3 SIE, 2 cytopenia, 1 hi LFTs https://
5-19-2021: Olumiant (baricitinib) causes blood clots, herpes zoster, and it can't be used together with corticosteroids. Patients who beg for long-term Actemra are given steroids, the side effects might be blamed on the Actemra: https://t.co/vPFqp3lJ6C h