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Evaluation of drug-induced tissue injury by measuring alanine aminotransferase (ALT) activity in silkworm hemolymph

Overview of attention for article published in BMC Pharmacology and Toxicology, November 2012
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2 X users

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22 Mendeley
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Title
Evaluation of drug-induced tissue injury by measuring alanine aminotransferase (ALT) activity in silkworm hemolymph
Published in
BMC Pharmacology and Toxicology, November 2012
DOI 10.1186/2050-6511-13-13
Pubmed ID
Authors

Yoshinori Inagaki, Yasuhiko Matsumoto, Keiko Kataoka, Naoya Matsuhashi, Kazuhisa Sekimizu

Abstract

Our previous studies suggest silkworms can be used as model animals instead of mammals in pharmacologic studies to develop novel therapeutic medicines. We examined the usefulness of the silkworm larvae Bombyx mori as an animal model for evaluating tissue injury induced by various cytotoxic drugs. Drugs that induce hepatotoxic effects in mammals were injected into the silkworm hemocoel, and alanine aminotransferase (ALT) activity was measured in the hemolymph 1 day later.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 18%
Researcher 3 14%
Student > Bachelor 2 9%
Student > Ph. D. Student 2 9%
Professor 1 5%
Other 1 5%
Unknown 9 41%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 36%
Biochemistry, Genetics and Molecular Biology 4 18%
Medicine and Dentistry 1 5%
Unknown 9 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2012.
All research outputs
#15,557,505
of 23,881,329 outputs
Outputs from BMC Pharmacology and Toxicology
#230
of 450 outputs
Outputs of similar age
#113,969
of 185,580 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#8
of 12 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 450 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 185,580 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.