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Systematic investigation of insertional and deletional RNA-DNA differences in the human transcriptome

Overview of attention for article published in BMC Genomics, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

twitter
18 tweeters

Citations

dimensions_citation
17 Dimensions

Readers on

mendeley
27 Mendeley
citeulike
3 CiteULike
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Title
Systematic investigation of insertional and deletional RNA-DNA differences in the human transcriptome
Published in
BMC Genomics, January 2012
DOI 10.1186/1471-2164-13-616
Pubmed ID
Authors

Cai Chen, Ralf Bundschuh

Abstract

The genomic information which is transcribed into the primary RNA can be altered by RNA editing at the transcriptional or post-transcriptional level, which provides an effective way to create transcript diversity in an organism. Altering can occur through substitutional RNA editing or via the insertion or deletion of nucleotides relative to the original template. Taking advantage of recent high throughput sequencing technology combined with bioinformatics tools, several groups have recently studied the genome-wide substitutional RNA editing profiles in human. However, while insertional/deletional (indel) RNA editing is well known in several lower species, only very scarce evidence supports the existence of insertional editing events in higher organisms such as human, and no previous work has specifically focused on indel differences between RNA and their matching DNA in human. Here, we provide the first study to examine the possibility of genome-wide indel RNA-DNA differences in one human individual, NA12878, whose RNA and matching genome have been deeply sequenced.

Twitter Demographics

The data shown below were collected from the profiles of 18 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 2 7%
United States 2 7%
Colombia 1 4%
Unknown 22 81%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 33%
Student > Ph. D. Student 5 19%
Professor > Associate Professor 3 11%
Student > Bachelor 2 7%
Unspecified 1 4%
Other 3 11%
Unknown 4 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 52%
Computer Science 3 11%
Engineering 2 7%
Biochemistry, Genetics and Molecular Biology 1 4%
Unspecified 1 4%
Other 2 7%
Unknown 4 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 November 2012.
All research outputs
#2,249,987
of 15,219,199 outputs
Outputs from BMC Genomics
#1,052
of 8,652 outputs
Outputs of similar age
#21,005
of 151,333 outputs
Outputs of similar age from BMC Genomics
#1
of 20 outputs
Altmetric has tracked 15,219,199 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,652 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 151,333 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.