Title |
Multivitamin supplementation in HIV infected adults initiating antiretroviral therapy in Uganda: the protocol for a randomized double blinded placebo controlled efficacy trial
|
---|---|
Published in |
BMC Infectious Diseases, November 2012
|
DOI | 10.1186/1471-2334-12-304 |
Pubmed ID | |
Authors |
David Guwatudde, Amara E Ezeamama, Danstan Bagenda, Rachel Kyeyune, Fred Wabwire-Mangen, Henry Wamani, Ferdinand Mugusi, Donna Spiegelman, Molin Wang, Yukari C Manabe, Wafaie W Fawzi |
Abstract |
Use of multivitamin supplements during the pre-HAART era has been found to reduce viral load, enhance immune response, and generally improve clinical outcomes among HIV-infected adults. However, immune reconstitution is incomplete and significant mortality and opportunistic infections occur in spite of HAART. There is insufficient research information on whether multivitamin supplementation may be beneficial as adjunct therapy for HIV-infected individuals taking HAART. We propose to evaluate the efficacy of a single recommended daily allowance (RDA) of micronutrients (including vitamins B-complex, C, and E) in slowing disease progression among HIV-infected adults receiving HAART in Uganda. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Jamaica | 1 | <1% |
Ethiopia | 1 | <1% |
Netherlands | 1 | <1% |
Portugal | 1 | <1% |
Unknown | 130 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 31 | 23% |
Student > Bachelor | 20 | 15% |
Researcher | 15 | 11% |
Student > Ph. D. Student | 11 | 8% |
Student > Doctoral Student | 9 | 7% |
Other | 21 | 16% |
Unknown | 27 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 43 | 32% |
Nursing and Health Professions | 15 | 11% |
Social Sciences | 10 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 6% |
Immunology and Microbiology | 5 | 4% |
Other | 23 | 17% |
Unknown | 30 | 22% |