Title |
Molecular characterization of rotavirus isolates from select Canadian pediatric hospitals
|
---|---|
Published in |
BMC Infectious Diseases, November 2012
|
DOI | 10.1186/1471-2334-12-306 |
Pubmed ID | |
Authors |
Andrew McDermid, Nicole Le Saux, Elsie Grudeski, Julie A Bettinger, Kathy Manguiat, Scott A Halperin, Lily MacDonald, Pierre Déry, Joanne Embree, Wendy Vaudry, Timothy F Booth, Members of the Canadian Immunization Monitoring Program, Active (IMPACT) |
Abstract |
We report the first multi-site rotavirus genotype analysis in Canada. Prior to this study, there was a dearth of rotavirus G and P genotyping data in Canada. Publically funded universal rotavirus vaccination in Canada started in 2011 and has been introduced by four provinces to date. Uptake of rotavirus vaccines in Canada prior to 2012 has been very limited. The aim of this study was to describe the genotypes of rotavirus strains circulating in Canada prior to widespread implementation of rotavirus vaccine by genotyping samples collected from selected paediatric hospitals. Secondly we identified rotavirus strains that differed genetically from those included in the vaccines and which could affect vaccine effectiveness. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hungary | 1 | 3% |
Canada | 1 | 3% |
Brazil | 1 | 3% |
Unknown | 29 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 19% |
Student > Ph. D. Student | 5 | 16% |
Professor > Associate Professor | 4 | 13% |
Student > Master | 4 | 13% |
Student > Doctoral Student | 2 | 6% |
Other | 5 | 16% |
Unknown | 6 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 31% |
Agricultural and Biological Sciences | 6 | 19% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Immunology and Microbiology | 2 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 4 | 13% |
Unknown | 7 | 22% |