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Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments

Overview of attention for article published in BMC Cancer, November 2012
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Title
Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments
Published in
BMC Cancer, November 2012
DOI 10.1186/1471-2407-12-522
Pubmed ID
Authors

Linh Nguyen, Theodora Fifis, Caterina Malcontenti-Wilson, Lie Sam Chan, Patricia Nunes Luiza Costa, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Christopher Christophi

Abstract

Treatment of solid tumors with vascular disrupting agent OXi4503 results in over 90% tumor destruction. However, a thin rim of viable cells persists in the tumor periphery following treatment, contributing to subsequent recurrence. This study investigates inherent differences in the microenvironment of the tumor periphery that contribute to treatment resistance.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 1 3%
Germany 1 3%
Canada 1 3%
Unknown 36 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 21%
Student > Bachelor 6 15%
Researcher 4 10%
Student > Postgraduate 3 8%
Student > Master 3 8%
Other 9 23%
Unknown 6 15%
Readers by discipline Count As %
Medicine and Dentistry 12 31%
Agricultural and Biological Sciences 6 15%
Engineering 5 13%
Biochemistry, Genetics and Molecular Biology 3 8%
Business, Management and Accounting 1 3%
Other 5 13%
Unknown 7 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2012.
All research outputs
#20,172,971
of 22,685,926 outputs
Outputs from BMC Cancer
#6,481
of 8,249 outputs
Outputs of similar age
#158,752
of 178,791 outputs
Outputs of similar age from BMC Cancer
#107
of 114 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,249 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,791 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.