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Zebrafish: A complete animal model to enumerate the nanoparticle toxicity

Overview of attention for article published in Journal of Nanobiotechnology, August 2016
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Title
Zebrafish: A complete animal model to enumerate the nanoparticle toxicity
Published in
Journal of Nanobiotechnology, August 2016
DOI 10.1186/s12951-016-0217-6
Pubmed ID
Authors

Chiranjib Chakraborty, Ashish Ranjan Sharma, Garima Sharma, Sang-Soo Lee

Abstract

Presently, nanotechnology is a multi-trillion dollar business sector that covers a wide range of industries, such as medicine, electronics and chemistry. In the current era, the commercial transition of nanotechnology from research level to industrial level is stimulating the world's total economic growth. However, commercialization of nanoparticles might offer possible risks once they are liberated in the environment. In recent years, the use of zebrafish (Danio rerio) as an established animal model system for nanoparticle toxicity assay is growing exponentially. In the current in-depth review, we discuss the recent research approaches employing adult zebrafish and their embryos for nanoparticle toxicity assessment. Different types of parameters are being discussed here which are used to evaluate nanoparticle toxicity such as hatching achievement rate, developmental malformation of organs, damage in gill and skin, abnormal behavior (movement impairment), immunotoxicity, genotoxicity or gene expression, neurotoxicity, endocrine system disruption, reproduction toxicity and finally mortality. Furthermore, we have also highlighted the toxic effect of different nanoparticles such as silver nanoparticle, gold nanoparticle, and metal oxide nanoparticles (TiO2, Al2O3, CuO, NiO and ZnO). At the end, future directions of zebrafish model and relevant assays to study nanoparticle toxicity have also been argued.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 328 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 2 <1%
Mexico 1 <1%
Switzerland 1 <1%
Unknown 324 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 66 20%
Student > Master 58 18%
Researcher 39 12%
Student > Bachelor 30 9%
Student > Doctoral Student 20 6%
Other 50 15%
Unknown 65 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 56 17%
Agricultural and Biological Sciences 53 16%
Pharmacology, Toxicology and Pharmaceutical Science 24 7%
Environmental Science 20 6%
Chemistry 17 5%
Other 62 19%
Unknown 96 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2017.
All research outputs
#12,930,298
of 14,665,930 outputs
Outputs from Journal of Nanobiotechnology
#413
of 530 outputs
Outputs of similar age
#220,209
of 262,684 outputs
Outputs of similar age from Journal of Nanobiotechnology
#3
of 5 outputs
Altmetric has tracked 14,665,930 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 530 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.