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Zebrafish: A complete animal model to enumerate the nanoparticle toxicity

Overview of attention for article published in Journal of Nanobiotechnology, August 2016
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Title
Zebrafish: A complete animal model to enumerate the nanoparticle toxicity
Published in
Journal of Nanobiotechnology, August 2016
DOI 10.1186/s12951-016-0217-6
Pubmed ID
Authors

Chiranjib Chakraborty, Ashish Ranjan Sharma, Garima Sharma, Sang-Soo Lee

Abstract

Presently, nanotechnology is a multi-trillion dollar business sector that covers a wide range of industries, such as medicine, electronics and chemistry. In the current era, the commercial transition of nanotechnology from research level to industrial level is stimulating the world's total economic growth. However, commercialization of nanoparticles might offer possible risks once they are liberated in the environment. In recent years, the use of zebrafish (Danio rerio) as an established animal model system for nanoparticle toxicity assay is growing exponentially. In the current in-depth review, we discuss the recent research approaches employing adult zebrafish and their embryos for nanoparticle toxicity assessment. Different types of parameters are being discussed here which are used to evaluate nanoparticle toxicity such as hatching achievement rate, developmental malformation of organs, damage in gill and skin, abnormal behavior (movement impairment), immunotoxicity, genotoxicity or gene expression, neurotoxicity, endocrine system disruption, reproduction toxicity and finally mortality. Furthermore, we have also highlighted the toxic effect of different nanoparticles such as silver nanoparticle, gold nanoparticle, and metal oxide nanoparticles (TiO2, Al2O3, CuO, NiO and ZnO). At the end, future directions of zebrafish model and relevant assays to study nanoparticle toxicity have also been argued.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 390 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 <1%
Portugal 1 <1%
Switzerland 1 <1%
Unknown 387 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 70 18%
Student > Master 67 17%
Researcher 43 11%
Student > Bachelor 33 8%
Student > Doctoral Student 21 5%
Other 60 15%
Unknown 96 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 60 15%
Agricultural and Biological Sciences 51 13%
Pharmacology, Toxicology and Pharmaceutical Science 28 7%
Environmental Science 22 6%
Chemistry 19 5%
Other 78 20%
Unknown 132 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2017.
All research outputs
#20,337,788
of 22,883,326 outputs
Outputs from Journal of Nanobiotechnology
#1,228
of 1,424 outputs
Outputs of similar age
#300,080
of 343,760 outputs
Outputs of similar age from Journal of Nanobiotechnology
#4
of 5 outputs
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So far Altmetric has tracked 1,424 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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