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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines
|
|---|---|
| Published in |
Genome Medicine, November 2012
|
| DOI | 10.1186/gm387 |
| Pubmed ID | |
| Authors |
Pelin Akan, Andrey Alexeyenko, Paul Igor Costea, Lilia Hedberg, Beata Werne Solnestam, Sverker Lundin, Jimmie Hällman, Emma Lundberg, Mathias Uhlén, Joakim Lundeberg |
| Abstract |
We here present a comparative genome, transcriptome and functional network analysis of three human cancer cell lines (A431, U251MG and U2OS), and investigate their relation to protein expression. Gene copy numbers significantly influenced corresponding transcript levels; their effect on protein levels was less pronounced. We focused on genes with altered mRNA and/or protein levels to identify those active in tumor maintenance. We provide comprehensive information for the three genomes and demonstrate the advantage of integrative analysis for identifying tumor-related genes amidst numerous background mutations by relating genomic variation to expression/protein abundance data and use gene networks to reveal implicated pathways. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 18% |
| Denmark | 1 | 9% |
| Montenegro | 1 | 9% |
| France | 1 | 9% |
| Sweden | 1 | 9% |
| United Kingdom | 1 | 9% |
| United States | 1 | 9% |
| Unknown | 3 | 27% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 45% |
| Scientists | 5 | 45% |
| Science communicators (journalists, bloggers, editors) | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 2 | 2% |
| Korea, Republic of | 1 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 107 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 27% |
| Researcher | 24 | 21% |
| Student > Master | 17 | 15% |
| Student > Bachelor | 11 | 10% |
| Professor > Associate Professor | 7 | 6% |
| Other | 16 | 14% |
| Unknown | 8 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 37% |
| Biochemistry, Genetics and Molecular Biology | 32 | 28% |
| Medicine and Dentistry | 12 | 11% |
| Computer Science | 6 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Other | 11 | 10% |
| Unknown | 7 | 6% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 June 2019.
All research outputs
#3,710,762
of 25,374,917 outputs
Outputs from Genome Medicine
#796
of 1,585 outputs
Outputs of similar age
#34,989
of 285,532 outputs
Outputs of similar age from Genome Medicine
#13
of 25 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,585 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.8. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,532 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.