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Nucleophosmin: from structure and function to disease development

Overview of attention for article published in BMC Molecular and Cell Biology, August 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
2 X users
patent
2 patents
wikipedia
1 Wikipedia page

Citations

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186 Dimensions

Readers on

mendeley
319 Mendeley
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Title
Nucleophosmin: from structure and function to disease development
Published in
BMC Molecular and Cell Biology, August 2016
DOI 10.1186/s12867-016-0073-9
Pubmed ID
Authors

Joseph K. Box, Nicolas Paquet, Mark N. Adams, Didier Boucher, Emma Bolderson, Kenneth J. O’Byrne, Derek J. Richard

Abstract

Nucleophosmin (NPM1) is a critical cellular protein that has been implicated in a number of pathways including mRNA transport, chromatin remodeling, apoptosis and genome stability. NPM1 function is a critical requirement for normal cellular biology as is underlined in cancer where NPM1 is commonly overexpressed, mutated, rearranged and sporadically deleted. Consistent with a multifunctional role within the cell, NPM1 can function not only as a proto-oncogene but also as a tumor suppressor. The aim of this review is to look at the less well-described role of NPM1 in the DNA repair pathways as well as the role of NPM1 in the regulation of apoptosis and its mutation in cancers.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 319 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 318 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 50 16%
Student > Bachelor 50 16%
Student > Master 40 13%
Researcher 37 12%
Student > Doctoral Student 16 5%
Other 37 12%
Unknown 89 28%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 121 38%
Agricultural and Biological Sciences 44 14%
Medicine and Dentistry 26 8%
Chemistry 8 3%
Immunology and Microbiology 6 2%
Other 18 6%
Unknown 96 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2021.
All research outputs
#5,165,888
of 25,374,647 outputs
Outputs from BMC Molecular and Cell Biology
#121
of 1,233 outputs
Outputs of similar age
#82,197
of 352,659 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#3
of 15 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,659 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.