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Factors that predict recurrence later than 5 years after initial treatment in operable breast cancer

Overview of attention for article published in World Journal of Surgical Oncology, January 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#12 of 1,700)
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
2 news outlets
twitter
4 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
27 Dimensions

Readers on

mendeley
66 Mendeley
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Title
Factors that predict recurrence later than 5 years after initial treatment in operable breast cancer
Published in
World Journal of Surgical Oncology, January 2016
DOI 10.1186/s12957-016-0988-0
Pubmed ID
Authors

Wangchinda, Pattaraporn, Ithimakin, Suthinee, Pattaraporn Wangchinda, Suthinee Ithimakin

Abstract

Occasionally, breast cancer relapses more than 5 years after initial treatment, sometimes with highly aggressive disease in such late-recurring patients. This study investigated predictors of recurrence after more than 5 years in operable breast cancer. We retrospectively analyzed data from patients with recurrent breast cancer treated at Siriraj Hospital. Patients were divided into those whose relapse times were longer or shorter than 5 years. Factors that predicted late recurrence were analyzed in both the overall population and the luminal subgroup. Patterns of relapse, changes in biomarkers, and time to disease progression after first relapse were also recorded. We included 300 women whose breast cancers recurred between 2005 and 2013, of whom 180 had recurrence within 5 years of diagnosis and 120 later than 5 years (median time to recurrence: 45.43 months; range: 4.4-250.3 months). Tumors larger than 2 cm, lymph node metastasis, and high nuclear grade were related with early recurrence. Estrogen receptor-positive, progesterone receptor-positive, and HER2(-) disease predicted late recurrence. Almost all late-relapsing patients with luminal tumors had high estrogen receptor (ER(+)) titers (≥50 %) and HER2(-) disease. Liver and brain were the most common early recurrence sites. Biomarkers did not significantly change by time of recurrence. ER(+)/PR(+) and HER2(-) patients have higher risk of recurrence later than 5 years, especially in patients with high ER titer and low nuclear grade. Larger and node-positive tumors had higher risk of early recurrence.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 66 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 20%
Student > Ph. D. Student 11 17%
Student > Bachelor 7 11%
Researcher 7 11%
Other 7 11%
Other 7 11%
Unknown 14 21%
Readers by discipline Count As %
Medicine and Dentistry 23 35%
Biochemistry, Genetics and Molecular Biology 7 11%
Pharmacology, Toxicology and Pharmaceutical Science 6 9%
Computer Science 2 3%
Agricultural and Biological Sciences 2 3%
Other 10 15%
Unknown 16 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2021.
All research outputs
#1,245,713
of 19,157,212 outputs
Outputs from World Journal of Surgical Oncology
#12
of 1,700 outputs
Outputs of similar age
#25,144
of 274,412 outputs
Outputs of similar age from World Journal of Surgical Oncology
#1
of 12 outputs
Altmetric has tracked 19,157,212 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,700 research outputs from this source. They receive a mean Attention Score of 1.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,412 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.