Title |
Colostrum supplementation protects against exercise - induced oxidative stress in skeletal muscle in mice
|
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Published in |
BMC Research Notes, November 2012
|
DOI | 10.1186/1756-0500-5-649 |
Pubmed ID | |
Authors |
Mahenderan Appukutty, Ammu Kutty Radhakrishnan, Kalavathy Ramasamy, Rajesh Ramasamy, Abu Bakar Abdul Majeed, Mohd Ismail Noor, Nik Shanita Safii, Poh Bee Koon, Karuthan Chinna, Nagaraja Haleagrahara |
Abstract |
This study examined the effects of bovine colostrum on exercise -induced modulation of antioxidant parameters in skeletal muscle in mice. Adult male BALB/c mice were randomly divided into four groups (control, colostrum alone, exercise and exercise with colostrum) and each group had three subgroups (day 0, 21 and 42). Colostrum groups of mice were given a daily oral supplement of 50 mg/kg body weight of bovine colostrum and the exercise group of mice were made to exercise on the treadmill for 30 minutes per day. Total antioxidants, lipid hydroperoxides, xanthine oxidase and super oxide dismutase level was assayed from the homogenate of hind limb skeletal muscle. |
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