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The epidemiology of adverse drug events and medication errors among psychiatric inpatients in Japan: the JADE study

Overview of attention for article published in BMC Psychiatry, August 2016
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Title
The epidemiology of adverse drug events and medication errors among psychiatric inpatients in Japan: the JADE study
Published in
BMC Psychiatry, August 2016
DOI 10.1186/s12888-016-1009-0
Pubmed ID
Authors

Nobutaka Ayani, Mio Sakuma, Takeshi Morimoto, Toshiaki Kikuchi, Koichiro Watanabe, Jin Narumoto, Kenji Fukui

Abstract

Knowledge of the epidemiology of adverse drug events (ADEs) and medication errors in psychiatric inpatients is limited outside Western countries. The nature of ADEs and medication errors are important for improving the quality of care worldwide; therefore, we conducted the Japan Adverse Drug Events Study, a series of cohort studies at several settings in Japan. This report included 448 inpatients with 22,733 patient-days in a psychiatric hospital and psychiatric units at a tertiary care teaching hospital over 1 year. Four psychiatrists and two other physicians reviewed all medical charts and related documents to identify suspected incidents. The physicians later classified those incidents into ADEs, potential ADEs, medication errors, or exclusions and evaluated the severity and preventability if the incidents were events. During the study period, we identified 955 ADEs and 398 medication errors (incidence: 42.0 and 17.5 per 1000 patient-days, respectively). Among ADEs, 1.4 %, 28 %, and 71 % were life-threatening, serious, and significant, respectively. Antipsychotics were associated with half of all ADEs. The incidence of medication errors was higher in medical care units than in acute and nursing care units (40.9, 15.6, and 17.4 per 1000 patient-days, respectively). The monitoring and ordering stages were the most common error stages (39 % and 34 % of all medication errors, respectively), and 76 % of medication errors with ADEs were found at the monitoring stage. Non-psychiatric drugs were three times as likely to cause ADEs with errors compared to psychiatric drugs. Antipsychotic use, inadequate monitoring, and treatment of physical ailments by psychiatrists may contribute to the high incidence of medication errors and ADEs among psychiatric inpatients in Japan. Psychiatrists should be cautious in prescribing antipsychotics or unfamiliar medications for physical problems in their psychiatric patients, and should monitor patients after medication administration.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 88 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 18%
Student > Ph. D. Student 11 13%
Researcher 6 7%
Student > Postgraduate 6 7%
Student > Bachelor 6 7%
Other 22 25%
Unknown 21 24%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 17 19%
Medicine and Dentistry 17 19%
Nursing and Health Professions 15 17%
Social Sciences 3 3%
Psychology 3 3%
Other 7 8%
Unknown 26 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2018.
All research outputs
#7,546,906
of 23,866,543 outputs
Outputs from BMC Psychiatry
#2,548
of 4,936 outputs
Outputs of similar age
#114,634
of 340,263 outputs
Outputs of similar age from BMC Psychiatry
#43
of 90 outputs
Altmetric has tracked 23,866,543 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 4,936 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.9. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,263 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.