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A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated…

Overview of attention for article published in BMC Genomics, November 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users

Citations

dimensions_citation
35 Dimensions

Readers on

mendeley
67 Mendeley
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Title
A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration
Published in
BMC Genomics, November 2012
DOI 10.1186/1471-2164-13-677
Pubmed ID
Authors

Li Zhou, Gulietta M Pupo, Priyanka Gupta, Bing Liu, Sieu L Tran, Raany Rahme, Bin Wang, Rejane Rua, Helen Rizos, Adam Carroll, Murray J Cairns, Nitin K Saksena

Abstract

HIV-associated dementia (HAD) is the most common dementia type in young adults less than 40 years of age. Although the neurotoxins, oxidative/metabolic stress and impaired activity of neurotrophic factors are believed to be underlying reasons for the development of HAD, the genomic basis, which ultimately defines the virus-host interaction and leads to neurologic manifestation of HIV disease is lacking. Therefore, identifying HIV fingerprints on the host gene machinery and its regulation by microRNA holds a great promise and potential for improving our understanding of HAD pathogenesis, its diagnosis and therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Unknown 65 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 22%
Researcher 13 19%
Student > Master 10 15%
Student > Bachelor 7 10%
Other 4 6%
Other 9 13%
Unknown 9 13%
Readers by discipline Count As %
Medicine and Dentistry 14 21%
Agricultural and Biological Sciences 11 16%
Nursing and Health Professions 6 9%
Neuroscience 5 7%
Computer Science 3 4%
Other 13 19%
Unknown 15 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2012.
All research outputs
#3,533,272
of 22,687,320 outputs
Outputs from BMC Genomics
#1,337
of 10,617 outputs
Outputs of similar age
#36,108
of 277,211 outputs
Outputs of similar age from BMC Genomics
#55
of 372 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,617 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,211 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 372 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.