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Toward epigenetic and gene regulation models of specific language impairment: looking for links among growth, genes, and impairments

Overview of attention for article published in Journal of Neurodevelopmental Disorders, November 2012
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  • Good Attention Score compared to outputs of the same age (74th percentile)

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1 policy source
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Citations

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62 Dimensions

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112 Mendeley
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2 CiteULike
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Title
Toward epigenetic and gene regulation models of specific language impairment: looking for links among growth, genes, and impairments
Published in
Journal of Neurodevelopmental Disorders, November 2012
DOI 10.1186/1866-1955-4-27
Pubmed ID
Authors

Mabel L Rice

Abstract

Children with specific language impairment (SLI) are thought to have an inherited form of language impairment that spares other developmental domains. SLI shows strong heritability and recent linkage and association studies have replicated results for candidate genes. Regulatory regions of the genes may be involved. Behavioral growth models of language development of children with SLI reveal that the onset of language is delayed, and the growth trajectories of children with SLI parallel those of younger children without SLI. The rate of language acquisition decelerates in the pre-adolescent period, resulting in immature language levels for the children with SLI that persist into adolescence and beyond. Recent genetic and epigenetic discoveries and models relevant to language impairment are reviewed. T cell regulation of onset, acceleration, and deceleration signaling are described as potential conceptual parallels to the growth timing elements of language acquisition and impairment. A growth signaling disruption (GSD) hypothesis is proposed for SLI, which posits that faulty timing mechanisms at the cellular level, intrinsic to neurocortical functioning essential for language onset and growth regulation, are at the core of the growth outcomes of SLI. The GSD highlights the need to document and account for growth patterns over childhood and suggests needed directions for future investigation.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Netherlands 1 <1%
France 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 106 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 28 25%
Researcher 20 18%
Student > Master 14 13%
Student > Bachelor 14 13%
Student > Doctoral Student 7 6%
Other 19 17%
Unknown 10 9%
Readers by discipline Count As %
Psychology 35 31%
Neuroscience 13 12%
Social Sciences 10 9%
Linguistics 10 9%
Agricultural and Biological Sciences 10 9%
Other 19 17%
Unknown 15 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2016.
All research outputs
#6,384,139
of 22,687,320 outputs
Outputs from Journal of Neurodevelopmental Disorders
#249
of 474 outputs
Outputs of similar age
#66,625
of 276,400 outputs
Outputs of similar age from Journal of Neurodevelopmental Disorders
#3
of 4 outputs
Altmetric has tracked 22,687,320 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 474 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.6. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,400 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.