Title |
Yokukansan (TJ-54) for treatment of pervasive developmental disorder not otherwise specified and Asperger’s disorder: a 12-week prospective, open-label study
|
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Published in |
BMC Psychiatry, November 2012
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DOI | 10.1186/1471-244x-12-215 |
Pubmed ID | |
Authors |
Tsuyoshi Miyaoka, Rei Wake, Motohide Furuya, Kristian Liaury, Masa Ieda, Kazunori Kawakami, Keiko Tsuchie, Takuji Inagaki, Jun Horiguchi |
Abstract |
Numerous medications have been tested on patients with pervasive developmental disorder not otherwise specified (PDD-NOS) and Asperger's disorder. Although many of these medications have been demonstrated to be useful, no clear primary treatment for PDD-NOS and Asperger's disorder has emerged. Despite the efficacy of some of the medicines, the acceptability and side effects have proven to be barriers to their use. Recent studies indicate that the traditional Japanese herbal medicine yokukansan (TJ-54) may be safe and useful in treating behavioral and psychological symptoms in dementia and some neuropsychiatric disorders. We aimed at evaluating both the efficacy and safety of TJ-54 in patients with well-defined PDD-NOS and Asperger's disorder. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 5 | 45% |
United States | 1 | 9% |
Unknown | 5 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 10 | 91% |
Practitioners (doctors, other healthcare professionals) | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Unknown | 134 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 20 | 15% |
Researcher | 18 | 13% |
Student > Ph. D. Student | 13 | 10% |
Student > Doctoral Student | 13 | 10% |
Student > Bachelor | 12 | 9% |
Other | 26 | 19% |
Unknown | 34 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 39 | 29% |
Medicine and Dentistry | 18 | 13% |
Unspecified | 7 | 5% |
Nursing and Health Professions | 5 | 4% |
Neuroscience | 5 | 4% |
Other | 22 | 16% |
Unknown | 40 | 29% |