Title |
Finding quasi-modules of human and viral miRNAs: a case study of human cytomegalovirus (HCMV)
|
---|---|
Published in |
BMC Bioinformatics, December 2012
|
DOI | 10.1186/1471-2105-13-322 |
Pubmed ID | |
Authors |
Isana Veksler-Lublinsky, Yonat Shemer-Avni, Eti Meiri, Zvi Bentwich, Klara Kedem, Michal Ziv-Ukelson |
Abstract |
MicroRNAs (miRNAs) are important regulators of gene expression encoded by a variety of organisms, including viruses. Although the function of most of the viral miRNAs is currently unknown, there is evidence that both viral and host miRNAs contribute to the interactions between viruses and their hosts. miRNAs constitute a complex combinatorial network, where one miRNA may target many genes and one gene may be targeted by multiple miRNAs. In particular, viral and host miRNAs may also have mutual target genes. Based on published evidence linking viral and host miRNAs there are three modes of mutual regulation: competing, cooperating, and compensating modes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 5% |
Unknown | 20 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 43% |
Professor | 3 | 14% |
Student > Doctoral Student | 2 | 10% |
Student > Bachelor | 1 | 5% |
Student > Master | 1 | 5% |
Other | 3 | 14% |
Unknown | 2 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 29% |
Computer Science | 5 | 24% |
Medicine and Dentistry | 3 | 14% |
Biochemistry, Genetics and Molecular Biology | 3 | 14% |
Veterinary Science and Veterinary Medicine | 1 | 5% |
Other | 2 | 10% |
Unknown | 1 | 5% |