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Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes

Overview of attention for article published in Journal of Neuroinflammation, December 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

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2 X users
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1 patent

Citations

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54 Dimensions

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71 Mendeley
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Title
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes
Published in
Journal of Neuroinflammation, December 2012
DOI 10.1186/1742-2094-9-264
Pubmed ID
Authors

Miklós Sárvári, Erik Hrabovszky, Imre Kalló, Norbert Solymosi, István Likó, Nicole Berchtold, Carl Cotman, Zsolt Liposits

Abstract

The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of middle-aged ovariectomized rats, but not in young ones reflecting elevated expression of these genes in middle-aged, ovarian hormone deficient animals. Here, we explored the impact of menopause on the microglia phenotype capitalizing on the differential expression of macrophage-associated genes in quiescent and activated microglia.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 71 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 23%
Other 6 8%
Student > Bachelor 6 8%
Student > Doctoral Student 5 7%
Professor 5 7%
Other 13 18%
Unknown 20 28%
Readers by discipline Count As %
Neuroscience 11 15%
Agricultural and Biological Sciences 10 14%
Biochemistry, Genetics and Molecular Biology 6 8%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Medicine and Dentistry 4 6%
Other 13 18%
Unknown 23 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2023.
All research outputs
#7,114,794
of 24,727,020 outputs
Outputs from Journal of Neuroinflammation
#1,226
of 2,857 outputs
Outputs of similar age
#70,732
of 288,384 outputs
Outputs of similar age from Journal of Neuroinflammation
#7
of 24 outputs
Altmetric has tracked 24,727,020 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 2,857 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,384 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.