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DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice

Overview of attention for article published in Molecular Brain, December 2012
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3 X users

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74 Mendeley
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Title
DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice
Published in
Molecular Brain, December 2012
DOI 10.1186/1756-6606-5-42
Pubmed ID
Authors

Ruth Pidsley, Cathy Fernandes, Joana Viana, Jose L Paya-Cano, Lin Liu, Rebecca G Smith, Leonard C Schalkwyk, Jonathan Mill

Abstract

Insulin-like growth factor 2 (Igf2) is a paternally expressed imprinted gene regulating fetal growth, playing an integral role in the development of many tissues including the brain. The parent-of-origin specific expression of Igf2 is largely controlled by allele-specific DNA methylation at CTCF-binding sites in the imprinting control region (ICR), located immediately upstream of the neighboring H19 gene. Previously we reported evidence of a negative correlation between DNA methylation in this region and cerebellum weight in humans.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 3%
Japan 1 1%
Spain 1 1%
Unknown 70 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 22%
Student > Bachelor 12 16%
Student > Master 10 14%
Researcher 10 14%
Student > Postgraduate 3 4%
Other 8 11%
Unknown 15 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 24 32%
Agricultural and Biological Sciences 18 24%
Medicine and Dentistry 9 12%
Neuroscience 4 5%
Social Sciences 2 3%
Other 3 4%
Unknown 14 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2023.
All research outputs
#14,821,326
of 24,004,724 outputs
Outputs from Molecular Brain
#532
of 1,162 outputs
Outputs of similar age
#170,542
of 285,132 outputs
Outputs of similar age from Molecular Brain
#7
of 13 outputs
Altmetric has tracked 24,004,724 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,162 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,132 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.