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Mendeley readers
Attention Score in Context
| Title |
GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia
|
|---|---|
| Published in |
Journal of Neuroinflammation, December 2012
|
| DOI | 10.1186/1742-2094-9-268 |
| Pubmed ID | |
| Authors |
Bijay Parajuli, Yoshifumi Sonobe, Jun Kawanokuchi, Yukiko Doi, Mariko Noda, Hideyuki Takeuchi, Tetsuya Mizuno, Akio Suzumura |
| Abstract |
Microglia are resident macrophage-like cells in the central nervous system (CNS) and cause innate immune responses via the LPS receptors, Toll-like receptor (TLR) 4 and CD14, in a variety of neuroinflammatory disorders including bacterial infection, Alzheimer's disease, and amyotrophic lateral sclerosis. Granulocyte macrophage-colony stimulating factor (GM-CSF) activates microglia and induces inflammatory responses via binding to GM-CSF receptor complex composed of two different subunit GM-CSF receptor α (GM-CSFRα) and common β chain (βc). GM-CSF has been shown to be associated with neuroinflammatory responses in multiple sclerosis and Alzheimer's disease. However, the mechanisms how GM-CSF promotes neuroinflammation still remain unclear. |
Mendeley readers
The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 3% |
| Spain | 1 | <1% |
| Unknown | 142 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 38 | 26% |
| Student > Master | 23 | 16% |
| Researcher | 18 | 12% |
| Student > Bachelor | 17 | 12% |
| Student > Doctoral Student | 7 | 5% |
| Other | 13 | 9% |
| Unknown | 31 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 30 | 20% |
| Neuroscience | 21 | 14% |
| Medicine and Dentistry | 16 | 11% |
| Biochemistry, Genetics and Molecular Biology | 15 | 10% |
| Immunology and Microbiology | 12 | 8% |
| Other | 12 | 8% |
| Unknown | 41 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2018.
All research outputs
#8,647,454
of 25,654,806 outputs
Outputs from Journal of Neuroinflammation
#1,417
of 2,969 outputs
Outputs of similar age
#87,390
of 287,696 outputs
Outputs of similar age from Journal of Neuroinflammation
#9
of 24 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,969 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,696 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.