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Efficacy of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder previously treated with amphetamines: analyses from a randomized, double-blind, multicenter, placebo-cont…

Overview of attention for article published in BMC Pharmacology and Toxicology, December 2012
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Title
Efficacy of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder previously treated with amphetamines: analyses from a randomized, double-blind, multicenter, placebo-controlled titration study
Published in
BMC Pharmacology and Toxicology, December 2012
DOI 10.1186/2050-6511-13-18
Pubmed ID
Authors

Thomas Babcock, Bryan Dirks, Ben Adeyi, Brian Scheckner

Abstract

To examine the efficacy of lisdexamfetamine dimesylate (LDX) in adults with attention-deficit/hyperactivity disorder (ADHD) who remained symptomatic (ADHD Rating Scale IV [ADHD-RS-IV] total score >18) on amphetamine (AMPH) therapy (mixed AMPH salts and/or d-AMPH formulations) prior to enrollment in a 4-week placebo-controlled LDX trial vs the overall study population. In these post hoc analyses from a multicenter, randomized, double-blind, forced-dose titration study, clinical efficacy of LDX (30-70 mg/d) in adults with ADHD receiving AMPH treatment at screening vs the overall study population was evaluated. ADHD symptoms were assessed using the ADHD-RS-IV with adult prompts at screening, baseline (after prior treatment washout), and endpoint. Safety assessments included treatment-emergent adverse events (TEAEs), vital signs, laboratory findings, and electrocardiogram.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
United States 2 2%
Israel 1 1%
India 1 1%
Unknown 76 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 14 17%
Student > Master 11 13%
Researcher 10 12%
Student > Ph. D. Student 5 6%
Other 4 5%
Other 12 15%
Unknown 26 32%
Readers by discipline Count As %
Medicine and Dentistry 23 28%
Psychology 6 7%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Nursing and Health Professions 5 6%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 8 10%
Unknown 32 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 January 2013.
All research outputs
#17,489,487
of 25,654,806 outputs
Outputs from BMC Pharmacology and Toxicology
#270
of 488 outputs
Outputs of similar age
#194,807
of 289,767 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#9
of 14 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 488 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,767 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.