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Clinical review: Ketones and brain injury

Overview of attention for article published in Critical Care, January 2011
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

blogs
1 blog
twitter
40 tweeters
facebook
10 Facebook pages
wikipedia
3 Wikipedia pages
reddit
1 Redditor
video
3 video uploaders

Citations

dimensions_citation
85 Dimensions

Readers on

mendeley
198 Mendeley
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Title
Clinical review: Ketones and brain injury
Published in
Critical Care, January 2011
DOI 10.1186/cc10020
Pubmed ID
Authors

Hayden White, Balasubramanian Venkatesh

Abstract

Although much feared by clinicians, the ability to produce ketones has allowed humans to withstand prolonged periods of starvation. At such times, ketones can supply up to 50% of basal energy requirements. More interesting, however, is the fact that ketones can provide as much as 70% of the brain's energy needs, more efficiently than glucose. Studies suggest that during times of acute brain injury, cerebral uptake of ketones increases significantly. Researchers have thus attempted to attenuate the effects of cerebral injury by administering ketones exogenously. Hypertonic saline is commonly utilized for management of intracranial hypertension following cerebral injury. A solution containing both hypertonic saline and ketones may prove ideal for managing the dual problems of refractory intracranial hypertension and low cerebral energy levels. The purpose of the present review is to explore the physiology of ketone body utilization by the brain in health and in a variety of neurological conditions, and to discuss the potential for ketone supplementation as a therapeutic option in traumatic brain injury.

Twitter Demographics

The data shown below were collected from the profiles of 40 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 198 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Brazil 3 2%
Australia 1 <1%
United Kingdom 1 <1%
Mexico 1 <1%
Chile 1 <1%
Unknown 188 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 33 17%
Student > Bachelor 32 16%
Researcher 27 14%
Student > Ph. D. Student 24 12%
Student > Postgraduate 16 8%
Other 51 26%
Unknown 15 8%
Readers by discipline Count As %
Medicine and Dentistry 79 40%
Agricultural and Biological Sciences 23 12%
Biochemistry, Genetics and Molecular Biology 19 10%
Nursing and Health Professions 16 8%
Neuroscience 16 8%
Other 27 14%
Unknown 18 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2021.
All research outputs
#616,391
of 19,044,106 outputs
Outputs from Critical Care
#475
of 5,552 outputs
Outputs of similar age
#6,509
of 273,951 outputs
Outputs of similar age from Critical Care
#7
of 225 outputs
Altmetric has tracked 19,044,106 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,552 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.4. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,951 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 225 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.