Title |
Evolution of cichlid vision via trans-regulatory divergence
|
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Published in |
BMC Ecology and Evolution, December 2012
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DOI | 10.1186/1471-2148-12-251 |
Pubmed ID | |
Authors |
Kelly E O’Quin, Jane E Schulte, Zil Patel, Nadia Kahn, Zan Naseer, Helena Wang, Matthew A Conte, Karen L Carleton |
Abstract |
Phenotypic evolution may occur through mutations that affect either the structure or expression of protein-coding genes. Although the evolution of color vision has historically been attributed to structural mutations within the opsin genes, recent research has shown that opsin regulatory mutations can also tune photoreceptor sensitivity and color vision. Visual sensitivity in African cichlid fishes varies as a result of the differential expression of seven opsin genes. We crossed cichlid species that express different opsin gene sets and scanned their genome for expression Quantitative Trait Loci (eQTL) responsible for these differences. Our results shed light on the role that different structural, cis-, and trans-regulatory mutations play in the evolution of color vision. |
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Mendeley readers
Geographical breakdown
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