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Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3?

Overview of attention for article published in BMC Medicine, January 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

twitter
45 tweeters
facebook
14 Facebook pages
googleplus
2 Google+ users

Citations

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38 Dimensions

Readers on

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87 Mendeley
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Title
Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3?
Published in
BMC Medicine, January 2013
DOI 10.1186/1741-7015-11-5
Pubmed ID
Authors

Michel de Lorgeril, Patricia Salen, Pascal Defaye, Mikael Rabaeus

Abstract

Early randomized controlled trials (RCTs) demonstrated the health benefits of omega-3 fatty acids (n-3), whereas recent RCTs were negative. We now address the issue, focusing on the temporal changes having occurred: most patients in recent RCTs are no longer n-3 deficient and the vast majority are now treated with statins. Recent RCTs testing n-3 against arrhythmias suggest that n-3 reduce the risk only in patients not taking a statin. Other recent RCTs in secondary prevention were negative although, in a post-hoc analysis separating statin users and non-users, non-significant protection of n-3 was observed among statin non-users whereas statin users had no effect. Recent RCTs testing statins - after the implementation of the New Clinical Trial Regulation in 2007 - are negative (or flawed) suggesting that the lack of effect of n-3 cannot be attributed to a parallel protection by statins. Finally, statins favor the metabolism of omega-6 fatty acids (n-6), which in turn inhibits n-3 and, contrary to n-3, they increase insulin resistance and the risk of diabetes. Thus, n-3 and statins are counteractive at several levels and statins appear to inhibit n-3.

Twitter Demographics

The data shown below were collected from the profiles of 45 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Brazil 1 1%
Unknown 85 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 17 20%
Other 12 14%
Student > Master 10 11%
Researcher 8 9%
Student > Postgraduate 7 8%
Other 22 25%
Unknown 11 13%
Readers by discipline Count As %
Medicine and Dentistry 38 44%
Agricultural and Biological Sciences 8 9%
Biochemistry, Genetics and Molecular Biology 7 8%
Nursing and Health Professions 7 8%
Social Sciences 2 2%
Other 10 11%
Unknown 15 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 35. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2019.
All research outputs
#958,010
of 22,691,736 outputs
Outputs from BMC Medicine
#683
of 3,400 outputs
Outputs of similar age
#8,563
of 280,650 outputs
Outputs of similar age from BMC Medicine
#17
of 72 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,400 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.6. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,650 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.