Title |
Identification of prognostic factors in canine mammary malignant tumours: a multivariable survival study
|
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Published in |
BMC Veterinary Research, January 2013
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DOI | 10.1186/1746-6148-9-1 |
Pubmed ID | |
Authors |
Andreia A Santos, Célia C Lopes, Jorge R Ribeiro, Liliana R Martins, Joana C Santos, Irina F Amorim, Fátima Gärtner, Augusto J Matos |
Abstract |
Although several histopathological and clinical features of canine mammary gland tumours have been widely studied from a prognostic standpoint, considerable variations in tumour individual biologic behaviour difficult the definition of accurate prognostic factors. It has been suggested that the malignant behaviour of tumours is the end result of several alterations in cellular physiology that culminate in tumour growth and spread. Accordingly, the aim of this study was to determine, using a multivariable model, the independent prognostic value of several immunohistochemically detected tumour-associated molecules, such as MMP-9 and uPA in stromal cells and Ki-67, TIMP-2 and VEGF in cancer cells. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 20% |
United States | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Portugal | 1 | <1% |
Italy | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 173 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 30 | 17% |
Student > Postgraduate | 19 | 11% |
Student > Doctoral Student | 18 | 10% |
Researcher | 15 | 8% |
Student > Bachelor | 15 | 8% |
Other | 47 | 27% |
Unknown | 33 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 75 | 42% |
Medicine and Dentistry | 34 | 19% |
Agricultural and Biological Sciences | 23 | 13% |
Biochemistry, Genetics and Molecular Biology | 3 | 2% |
Immunology and Microbiology | 2 | 1% |
Other | 4 | 2% |
Unknown | 36 | 20% |