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Mendeley readers
Attention Score in Context
Title |
Attenuation of multiple Nef functions in HIV-1 elite controllers
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---|---|
Published in |
Retrovirology, January 2013
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DOI | 10.1186/1742-4690-10-1 |
Pubmed ID | |
Authors |
Philip Mwimanzi, Tristan J Markle, Eric Martin, Yoko Ogata, Xiaomei T Kuang, Michiyo Tokunaga, Macdonald Mahiti, Florencia Pereyra, Toshiyuki Miura, Bruce D Walker, Zabrina L Brumme, Mark A Brockman, Takamasa Ueno |
Abstract |
Impaired HIV-1 Gag, Pol, and Env function has been described in elite controllers (EC) who spontaneously suppress plasma viremia to < 50 RNA copies/mL; however, activity of the accessory protein Nef remains incompletely characterized. We examined the ability of 91 Nef clones, isolated from plasma of 45 EC and 46 chronic progressors (CP), to down-regulate HLA class I and CD4, up-regulate HLA class II invariant chain (CD74), enhance viral infectivity, and stimulate viral replication in PBMC. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 60% |
Spain | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 3% |
United Kingdom | 2 | 3% |
France | 1 | 1% |
Brazil | 1 | 1% |
South Africa | 1 | 1% |
Saudi Arabia | 1 | 1% |
United States | 1 | 1% |
Unknown | 66 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 18 | 24% |
Researcher | 16 | 21% |
Student > Master | 9 | 12% |
Student > Bachelor | 7 | 9% |
Student > Postgraduate | 5 | 7% |
Other | 13 | 17% |
Unknown | 7 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 26 | 35% |
Immunology and Microbiology | 16 | 21% |
Biochemistry, Genetics and Molecular Biology | 11 | 15% |
Medicine and Dentistry | 8 | 11% |
Chemistry | 2 | 3% |
Other | 3 | 4% |
Unknown | 9 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2024.
All research outputs
#16,032,818
of 25,769,258 outputs
Outputs from Retrovirology
#736
of 1,277 outputs
Outputs of similar age
#181,313
of 292,371 outputs
Outputs of similar age from Retrovirology
#12
of 28 outputs
Altmetric has tracked 25,769,258 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,277 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 292,371 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.