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Comment on Kokshoorn, B, and Blankers, BJ ‘Response to Grisedale, KS and van Daal, A: comparison of STR profiling from low template DNA extracts with and without the consensus profiling method’

Overview of attention for article published in Investigative Genetics, January 2013
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Title
Comment on Kokshoorn, B, and Blankers, BJ ‘Response to Grisedale, KS and van Daal, A: comparison of STR profiling from low template DNA extracts with and without the consensus profiling method’
Published in
Investigative Genetics, January 2013
DOI 10.1186/2041-2223-4-2
Pubmed ID
Authors

Kelly Grisedale, Angela van Daal

Abstract

Kokshoorn and Blankers responded to our recent article by saying that replicate analysis and consensus profiling of low template samples was best in terms of reliability and objectivity. We agree that the consensus approach has benefits, particularly in eliminating non-repeating spurious alleles from the final profile. However, with the development of statistical models that can accommodate stochastic effects and allele drop in, it may be beneficial to perform a single amplification with three times the amount of template, since much information is lost from the profile using the consensus approach.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 50%
Professor > Associate Professor 1 25%
Student > Ph. D. Student 1 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 50%
Chemistry 1 25%
Medicine and Dentistry 1 25%