Title |
Animal model of Mycoplasma fermentans respiratory infection
|
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Published in |
BMC Research Notes, January 2013
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DOI | 10.1186/1756-0500-6-9 |
Pubmed ID | |
Authors |
Antonio Yáñez, Azucena Martínez-Ramos, Teresa Calixto, Francisco Javier González-Matus, José Antonio Rivera-Tapia, Silvia Giono, Constantino Gil, Lilia Cedillo |
Abstract |
Mycoplasma fermentans has been associated with respiratory, genitourinary tract infections and rheumatoid diseases but its role as pathogen is controversial. The purpose of this study was to probe that Mycoplasma fermentans is able to produce respiratory tract infection and migrate to several organs on an experimental infection model in hamsters. One hundred and twenty six hamsters were divided in six groups (A-F) of 21 hamsters each. Animals of groups A, B, C were intratracheally injected with one of the mycoplasma strains: Mycoplasma fermentans P 140 (wild strain), Mycoplasma fermentans PG 18 (type strain) or Mycoplasma pneumoniae Eaton strain. Groups D, E, F were the negative, media, and sham controls. Fragments of trachea, lungs, kidney, heart, brain and spleen were cultured and used for the histopathological study. U frequency test was used to compare recovery of mycoplasmas from organs. |
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United States | 2 | 100% |
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Members of the public | 2 | 100% |
Mendeley readers
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Mexico | 1 | 5% |
Unknown | 19 | 95% |
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Student > Bachelor | 4 | 20% |
Student > Master | 3 | 15% |
Professor | 2 | 10% |
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Unknown | 2 | 10% |
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Social Sciences | 1 | 5% |
Other | 1 | 5% |
Unknown | 2 | 10% |