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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Murraya koenigii leaf extract inhibits proteasome activity and induces cell death in breast cancer cells
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, January 2013
|
| DOI | 10.1186/1472-6882-13-7 |
| Pubmed ID | |
| Authors |
Bindu Noolu, Rajanna Ajumeera, Anitha Chauhan, Balakrishna Nagalla, Raghunath Manchala, Ayesha Ismail |
| Abstract |
Inhibition of the proteolytic activity of 26S proteasome, the protein-degrading machine, is now considered a novel and promising approach for cancer therapy. Interestingly, proteasome inhibitors have been demonstrated to selectively kill cancer cells and also enhance the sensitivity of tumor cells to chemotherapeutic agents. Recently, polyphenols/flavonoids have been reported to inhibit proteasome activity. Murraya koenigii Spreng, a medicinally important herb of Indian origin, has been used for centuries in the Ayurvedic system of medicine. Here we show that Murraya koenigii leaves (curry leaves), a rich source of polyphenols, inhibit the proteolytic activity of the cancer cell proteasome, and cause cell death. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 30% |
| Canada | 1 | 10% |
| Maldives | 1 | 10% |
| Ukraine | 1 | 10% |
| Unknown | 4 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 90% |
| Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 1 | <1% |
| India | 1 | <1% |
| Unknown | 102 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 15 | 14% |
| Student > Ph. D. Student | 14 | 13% |
| Student > Bachelor | 13 | 13% |
| Researcher | 10 | 10% |
| Student > Doctoral Student | 5 | 5% |
| Other | 16 | 15% |
| Unknown | 31 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 13% |
| Biochemistry, Genetics and Molecular Biology | 12 | 12% |
| Chemistry | 9 | 9% |
| Medicine and Dentistry | 9 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
| Other | 19 | 18% |
| Unknown | 36 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2022.
All research outputs
#4,195,335
of 25,809,966 outputs
Outputs from BMC Complementary Medicine and Therapies
#767
of 3,996 outputs
Outputs of similar age
#40,851
of 293,658 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#12
of 73 outputs
Altmetric has tracked 25,809,966 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,996 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 293,658 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.