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Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

Overview of attention for article published in Genome Medicine, January 2013
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1 tweeter

Citations

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129 Dimensions

Readers on

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63 Mendeley
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1 CiteULike
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Title
Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1
Published in
Genome Medicine, January 2013
DOI 10.1186/gm405
Pubmed ID
Abstract

Organic anion transporting polypeptide (OATP) 1B1, OATP1B3, and OATP2B1 (encoded by SLCO1B1, SLCO1B3, SLCO2B1) mediate the hepatic uptake of endogenous compounds like bile acids and of drugs, for example, the lipid-lowering atorvastatin, thereby influencing hepatobiliary elimination. Here we systematically elucidated the contribution of SLCO variants on expression of the three hepatic OATPs under consideration of additional important covariates.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Korea, Republic of 1 2%
Finland 1 2%
Canada 1 2%
Japan 1 2%
Unknown 58 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 19%
Student > Ph. D. Student 12 19%
Student > Master 7 11%
Other 6 10%
Student > Doctoral Student 4 6%
Other 11 17%
Unknown 11 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 30%
Medicine and Dentistry 13 21%
Pharmacology, Toxicology and Pharmaceutical Science 9 14%
Biochemistry, Genetics and Molecular Biology 5 8%
Chemistry 2 3%
Other 2 3%
Unknown 13 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2013.
All research outputs
#3,076,756
of 4,507,280 outputs
Outputs from Genome Medicine
#420
of 467 outputs
Outputs of similar age
#193,052
of 284,039 outputs
Outputs of similar age from Genome Medicine
#23
of 23 outputs
Altmetric has tracked 4,507,280 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.6. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,039 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.