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Development and validation of ultra-performance liquid chromatographic method with tandem mass spectrometry for determination of lenalidomide in rabbit and human plasma

Overview of attention for article published in BMC Chemistry, January 2013
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Title
Development and validation of ultra-performance liquid chromatographic method with tandem mass spectrometry for determination of lenalidomide in rabbit and human plasma
Published in
BMC Chemistry, January 2013
DOI 10.1186/1752-153x-7-7
Pubmed ID
Authors

Muzaffar Iqbal, Tanveer A Wani, Nasr Y Khalil, Ibrahim A Darwish

Abstract

Lenalidomide (LND) is a potent novel thalidomide analog which demonstrated remarkable clinical activity in treatment of multiple myeloma disease via a multiple-pathways mechanism. Validated sensitive method with high throughput is required for the determination of lenalidomide for pharmacokinetics and toxicokinetic studies. Ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) is a preeminent analytical tool for rapid biomedical analysis.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 6%
Unknown 15 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 25%
Other 2 13%
Student > Postgraduate 2 13%
Lecturer 1 6%
Professor 1 6%
Other 3 19%
Unknown 3 19%
Readers by discipline Count As %
Chemistry 3 19%
Medicine and Dentistry 3 19%
Biochemistry, Genetics and Molecular Biology 2 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 13%
Agricultural and Biological Sciences 2 13%
Other 0 0%
Unknown 4 25%