Title |
The history of neuromyelitis optica
|
---|---|
Published in |
Journal of Neuroinflammation, January 2013
|
DOI | 10.1186/1742-2094-10-8 |
Pubmed ID | |
Authors |
Sven Jarius, Brigitte Wildemann |
Abstract |
The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO). While the history of classical multiple sclerosis has been extensively studied, only little is known about the history of NMO. In the present article, we provide a comprehensive review of the early history of this rare but intriguing syndrome. We trace the origins of the concept of NMO in the 19th century medical literature and follow its evolution throughout the 20th and into the 21st century. Finally, we discuss recent proposals to revise the concept of NMO and explain why there is indeed a need for a more systematic and descriptive nomenclature. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
United Kingdom | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 3 | 1% |
Italy | 1 | <1% |
Germany | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 273 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 37 | 13% |
Student > Master | 31 | 11% |
Student > Postgraduate | 30 | 11% |
Other | 28 | 10% |
Student > Bachelor | 25 | 9% |
Other | 64 | 23% |
Unknown | 65 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 106 | 38% |
Neuroscience | 35 | 13% |
Agricultural and Biological Sciences | 21 | 8% |
Biochemistry, Genetics and Molecular Biology | 16 | 6% |
Immunology and Microbiology | 7 | 3% |
Other | 20 | 7% |
Unknown | 75 | 27% |